畢彩豐

畢彩豐

畢彩豐,1956年10月出生,山東平度市人,中共黨員,博士學位,現任中國海洋大學化學化工學院教授, 博士生導師。完成省級鑑定項目4項,都達到了國際先進水平。主持完成省、市科研項目7項;完成套用開發項目12項,累計創造經濟效益過億元。完成的醫藥中間體、原料藥、精細化工新產品在國內外市場頗具競爭力。 已合成、表征了200多個新的化合物,發表論文60多篇,其中SCI收錄6篇。目前在研項目5項,其中青島市科技計畫項目1項;海大蘭太科技項目2項;海洋配位化學1項、新型Schiff鹼配合物的合成與套用研究1項。

基本信息

人物經歷

1982年 本科畢業於山東大學化學系;

2001年7月博士畢業於中國原子能科學研究院。

1988年任中國海洋大學化學化工學院講師;1993年任副教授;1996年任教授。

1978-1982,山東大學無機化學專業,獲學士學位

1998-2001,中國原子能科學研究院核化學化工專業,獲博士學位

1993-1996,濟南大學化學化工學院副教授

1996-2002,濟南大學化學化工學院教授

2002-現在,中國海洋大學大學學院教授

主講課程

配位化學、 熱分析導論、有機合成前沿及本科生課程:無機化學、配位化學。

研究方向

精細化學品;

功能配合物;

海洋資源利用 。

醫藥及中間體合成;新型功能配合物的合成;海洋資源利用技術與工程;精細化學品合成。

主要研究方向:功能配合物化學、精細化學品化學。

主要貢獻

1.新型胺基酸希夫鹼銅配合物的合成及在抗腫瘤作用靶點-蛋白酶體中的套用,20971115,2010.1-2012.12,國家自然科學基金

2. 以小分子海洋生物活性物質為前軀物配合物的設計合成與抗腫瘤活性研究,21071134,2011.1-2013.12,國家自然科學基金

3. 油田採油綜合節水技研究與示範的子課題: 星型聚醯胺-胺型破乳劑體系的研製。(2006BABO4BO2) 國家十一五科技支撐計畫

4. 海洋赤潮毒素的毛細管電泳電化學線上快速檢測新技術和新儀器(2007AA09Z113),2007.10-2010.10,國家 863計畫

5. 頭孢類藥物及中間體合成。

近1. Qiang Wang, Caifeng Bi, Yuhua Fan, Xia Zhang,Jian Zuo and Sanbin Liu. A novel copper(Ⅱ) complex with Schiff base derived from o-vanillin and L-methionine: Synthesis and crystal structure. Russian Journal of Coordination Chemistry, 2011, 37(3): 228-234. SCI2. Yuhua Fan, Yufang Wang, Caifeng Bi, QiangWang, Xia Zhang. Synthesis, crystal structure, and fluorescence properties of a two-dimensional copper(Ⅱ) complex with Schiff base. Russian Journal of Coordination Chemistry, 2010, 36(7): 509-513. SCI3.?????Xinyu Liu, Yuhua Fan, Qiang Wang , Caifeng Bi and Yufang Wang. 1-[(Z)- (5- Methyl-2-pyridyl)iminiomethyl]-2-naphtholate.Acta Crystallographica Section E, 2010, 66: o309. SCI4. Jun Yang, Caifeng Bi, Tingting You and Yuhua Fan. Synthesis and crystal structure of 1-(2-(1H-Benzoimidazol-1-yl)ethyl-1H- benzoimidazol-3-ium Chloride Hydrate. Asian Journal of chemistry, 2010, 22(3):1689-1694. SCI5. Yan Xiao, Di Chen, Xia Zhang,Qiuzhi Cui, Yuhua Fan, Caifeng Bi, Qingping Dou. Molecular study on copper-mediated tumor proteasome inhibition and cell death. International Journal of Oncology,2010, 37(1):81-87. SCI 6. Xia Zhang, Michael Frezza, Vesna Milacic, LucaRonconi, Yuhua Fan, Caifeng Bi and Qingping Dou. Inhibition of tumor proteasome activity by gold- dithiocarbamato complexes via both redox-dependent and-independent processes. Journal of Cellular Biochemistry, 2010, 109:162-172. SCI 7. Yan Xiao, Caifeng Bi, Yuhua Fan, Shanbin Liu, Xia Zhang, Dongmei Zhang, Yilong Wang . Synthesis,characterization and bioactivity of Schiff base copper(Ⅱ) complexes derived from L-glutamine and L-asparagine. Journal of Coordination Chemistry, 2009, 62(18):3029-3039. SCI8. Qiang Wang, Caifeng Bi, Daqi Wang, Yuhua Fan. Dichlorido{N-[1- pyridyl] ethlidene]ethane-1,2-diamine}copper(Ⅱ). Acta Cryst. 2009, E65, m439 . SCI9. Qiang Wang, Caifeng Bi, Yuhua Fan. Tetra-μ-acetato-κ8O:O/-bis{[2-(2- furyl)- 1-(2-furylmethyl)-1H-benzimidazole-κN3]copper(Ⅱ)}. Acta Cryst. 2009. E65, m867-868. SCI10. Siquan Liu, Caifeng Bi, L.-Y.Chen and Yuhua Fan. 2-[(1,3-Benzothiazol-2-yl) iminomethyl] phenol, Acta Cryst. 2009. E65, o738. SCI11. Xinyu Liu, Yuhua Fan, Caifeng Bi, Yuan Gao. 2-Methoxy-6-[(Z)- [(5-methyl-2-pyridyl) iminomethyl]phenol. Acta Cryst. 2009, E65, o2170. SCI 12. Yan Xiao, Caifeng Bi , Yuhua Fan, Cindy Cui, Xia Zhang and Qingping Dou. L-glutamine Schiff base copper complex as a proteasome inhibitor and an apoptosis inducer in human cancer cells. International Journal of Oncology, 2008, 33: 1073-1079. SCI13. Xia Zhang, Caifeng Bi , Yuhua Fan, Cindy Cui, Di Chen, Yan Xiao and Qingping Dou. Induction of tumor cell apoptosis by taurine Schiff base copper complex is associated the with inhibition of proteasomal activity. International Journal of Molecular Medicine, 2008, 22: 677-682. SCI 14. Yuhua Fan , Feng Guo, Caifeng Bi, Dongmei Zhang , Yu Zhao, Jiakun Xu. Synthesis, characterization, and electrochemical studies on the interaction of binuclear Cu(Ⅱ) complex with DNA. Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry, 2008, 38(7): 573-576. SCI 15. Yuhua Fan, Zixian Gao, Caifeng Bi, Sitan Xie, Xia Zhang. Synthesis and thermal decomposition kinetics of La(Ⅲ) complex with unsymmetrical Schiff base ligand. Journal of Thermal Analysis and Calorimetry, 2008, 91(3):919-923. SCI16. Yuhua Fan , Yingying Li, Caifeng Bi, et al. Synthesis, characterization, and prohibitive action on free radical O2-· of β-phenylalanine Schiff base binuclear complexes. Russian Journal of Coordination Chemistry, 2008, 34(10):772-774. SCI17. Yuhua Fan, Qiang Wang, Caifeng Bi. Poly[tris(μ3-5-aminoisophthalato) diaquadicerium (Ⅲ)]. Acta Cryst. (2008). E64, m1326. SCI18. Yan Xiao, Caifeng Bi, Yuhua Fan, et al. 1,1/,5,5/-Tetramethyl-2,2/-diphenyl-4,4/- [p-phenyl-enebis(methylidymenitrilo)]di-1H-pyrazol-3(2H)-one. Acta Cryst. 2008, E64, o1479. SCI19. Caifeng Bi, Xia Zhang, Yuhua Fan, et al. Synthesis and thermal decomposition kinetics of uranium(Ⅵ) complex with unsymmetrical Schiff base ligand. Chinese Journal of Chemistry, 2008, 26(2): 265-268. SCI 20. Aidong Wang , Caifeng Bi , Yuhua Fan, et al. Structure and coordination environment of the zinc complex with vanillin of double-stranded helix. Russian Journal of Coordination Chemistry, 2008, 34(7): 475-479. SCI21. Yuhua Fan, Xuetao He, Caifeng Bi, Feng Guo, Yan Bao and Rong Chen. Synthesis, characterization and antibacterial activity of new rare-earth complexes with unsymmetrical Schiff base ligand. Russian Journal of Coordination Chemistry, 2007, 33(7):546-549. SCI22. Yuhua Fan, Yanna Zou, Caifeng Bi, Aidong Wang and Feng Guo. Synthesis, crystal structure and thermal decomposition kinetics of Zn(Ⅱ) complex with vanillin. Russian Journal of Coordination Chemistry, 2007, 33(8):582-587. SCI23. Caifeng Bi, Aidong Wang, Yuhua Fan, Yanna Zou, Xia Zhang. Synthesis, crystal structure and theoretical calculation of Ni (Ⅱ) complex with N,N′-1,2-cyclohexenylenebi s(salicy- lideneimine). Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry, 2007, 37(1) :67-71. SCI24. Caifeng Bi, Xiaokang Ai, Yuhua Fan, Shuangyu Bi, Sitan Xie. Synthesis and thermal decomposition kinetics of La(Ⅲ) complex with unsymmetrical Schiff base. Journal of the Chilean Chemical Society, 2007, 52(4): 1126-1128. SCI25.Lirong Yang, Caifeng Bi, Yuhua Fan. Crystal structure and thermodecomposition kinetics of copper(Ⅱ) ternary complex with o-vanillin-taurine Schiff -base and 1,10-phenanthroline. Asian Journal of Chemistry, 2007, 19(1) : 195-204. SCI26.Feng Guo, Caifeng Bi, Yuhua Fan, Yan Xiao, Xuetao He and Jiakun Xu. Synthesis, crystal structure and antibacterial properties of N-(2-Hydroxy-1- naphthalidene)-4-aminoantipyrine. Asian Journal of Chemistry, 2007, 19(3): 1846-1852. SCI27. Fan Yuhua, Bi Caifeng, Ai Xiaokang, Yaosen Xue, Xuetao He, Yan Xiao. Synthesis and thermal decomposition kinetics of Er(Ⅲ) complex with unsymmetrical Schiff base ligand. Journal of Coordination Chemistry. 2006, 59(14/20): 1575-1581. SCI28. Yuhua Fan, Caifeng Bi, Siquan Liu. Synthesis and thermal decomposition kinetics of Th (Ⅳ) complex with unsymmetrical Schiff base ligand. Journal of Radioanalytical and Nuclear Chemistry, 2006, 267(1): 89-93. SCI29. Yuhua Fan, Caifeng Bi. Synthesis, characterization and thermodecomposition kinetics of Sm(Ⅲ) complex with unsymmetrical Schiff base zwitterion ligand. Chinese Journal of Chemistry, 2006, 24(3): 371-374. SCI30. Yanna Zou, Yuhua Fan, Caifeng Bi. Synthesis and crystal structure of Zn (Ⅱ) complex with 2-aminopyridine and acetylacetone. Journal of Structural Chemistry, 2006, 25(3): 261-264. SCI31. Xiaokang Ai, Caifeng Bi, Yuhua Fan. 2-[(2-Aminophenylimino) (phenyl)-methyl]-4-chlorophenol.Acta Crystallographica Section E. 2006,E62, o3475-o3476. SCI32. Lirong Yang, Caifeng Bi, Yuhua Fan. Crystal structure and thermodecomposition kinetics of a three-dimensional supramolecular Mn comlplex with 8-hydroxyquinoline. Russian Journal of Coordination Chemistry, 2006, 32(7):504. SCI33. Caifeng Bi, Xiaokang Ai, Yuhua Fan. Synthesis, characterization and thermal decomposition kinetics of unsymmetrical Schiff base complex with samarium (Ⅲ). Journal of Rare Earths, 2006, 24(Suppl.):7-10. SCI期發表代表性文章

獲獎記錄

1990年獲教育部科技進步二等獎;

1991年獲國家星火二等獎;

1995年被評為全國優秀教師;

1995年享受國務院特殊津貼;

1997年被評為山東省專業技術拔尖人才;

2001年濟南市客座專業技術拔尖人才。

1989年獲山東省科技進步二等獎;

1990年獲山東省發明成果二等獎;

1991年獲國家星火二等獎;

1990年獲教育部科技進步二等獎;

1997年獲山東省教育廳科技進步三等獎。

1992年被評為國家建材局優秀青年科技工作者;

1994年獲山東省優秀青年知識分子稱號;

1995年被評為全國優秀教師;

1995年享受國務院特殊津貼;

1997年被評為山東省專業技術拔尖人才;

2001年濟南市客座專業技術拔尖人才。

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