許信剛

許信剛,男,1997年畢業於西北農業大學獸醫系獸醫專業(五年制),2000年獲預防獸醫學專業碩士學位,2005年獲臨床獸醫學博士學位,2005年晉升為副教授。為動物醫學系預防獸醫學教研室獸醫微生物學課程組教師。

承擔課程

承擔動物醫學和生物科學的“獸醫微生物學”、“動物微生物學”、“水產動物微生物學”等本科課程的主講。承擔碩士研究生的“高級獸醫微生物學”、“高級獸醫微生物學試驗技術”等課程的主講。

研究方向

動物病毒分子生物學。

代表性論著

1. Xin-Gang Xu, Zhi-Sheng Wang, Qi Zhang, Zhao-Cai Li, Li Ding, Wei Li, Hung-Yi Wu, Ching-Dong Chang, Long-Huw Lee, De-Wen Tong*, Hung-Jen Liu*. Baculovirus as a PRRSV and PCV2 bivalent vaccine vector: Baculovirus virions displaying simultaneously GP5 glycoprotein of PRRSV and capsid protein of PCV2. Journal of Virological Methods, 2012,179(2), 359-366.(IF=2.133)

2. Xin-Gang Xu,Hong-Ni Zhao, Qi Zhang, Li Ding, Zhao-Cai Li, Wei Li, De-Wen Tong*, Hung-Jen Liu *. Oral vaccination with attenuated Salmonella enterica serovar Typhimurium

expressing Cap protein of PCV2 and its immunogenicity in mouse and swine models . Veterinary Microbiology. 2012 ( Accepted). IF=3.256

3. Zhao-Cai Li, Xin-Gang Xu ( Contribute to this paper equally), Yong Huang , Li Ding, Zhi-Sheng Wang ,Gao-Shui Yu, Dan Xu, Wei Li, Dewen Tong*. Swainsonine activates mitochondria-mediated apoptotic pathway in human lung cancer A549 cells and retards the growth of lung cancer xenografts. International Journal of Biological Sciences, 2012. accepted(IF=3.2)

4. Li Ding, Xin-Gang Xu ( Contribute to this paper equally), Yong Huang , Zhao-Cai Li, Zhi-Sheng Wang ,Gao-Shui Yu, Dan Xu, Wei Li, Dewen Tong*. Transmissible gastroenteritis virus induces apoptosis through FasL and mitochondrion-mediated pathway dependent of viral replication. Veterinary Microbiology. 2012 ( Accepted). IF=3.256

5.Wei Li, XinGang Xu,Yong Huang, Zhaocai Li, Gaoshui Yu, Zhisheng Wang, Li Ding, Dewen Tong*. Establishment and evaluation of a stable steroidogenic goat luteal cell line . Theriogenology, 2012,( accepted) (IF= 2.045 )

6. Xin-Gang Xu, Zhi-Sheng Wang, Qi Zhang, Zhao-Cai Li, Hong-Ni Zhao, Wei Li, De-Wen Tong*, Hung-Jen Liu*. Baculovirus surface display of E envelope glycoprotein of Japanese encephalitis virus and its immunogenicity of the displayed proteins in mouse and swine models, Vaccine, 2011, 29(4):636-643. (IF=3.572)

7. Xin-Gang Xu, Zhi-Sheng Wang, Qi Zhang , Zhao-Cai Li, Kuan Zhang, Wei Li, De-Wen Tong*, Hung-Jen Liu*. Baculovirus virions displaying infectious bursal disease virus VP2 protein protect chickens against infectious bursal disease virus infection. Avian Diseases,2011, 55:223-229(SCI, IF=1.623)

8. Xin-Gang Xu , De-Wen Tong, Ming-Tang Chiou, Yao-Ching Hsieh, Wen-Ling Shih, Ching-Dong Chang, Ming-Huei Liao, Yan-Ming Zhang, Hung-Jen Liu*. Baculovirus surface display of NS3 nonstructural protein of classical swine fever virus. Journal of Virological Methods, 2009, (159)2: 259-264. (IF=2.133)

9. Xin-Gang Xu, Ming-Tang Chiou, Yan-Ming Zhang, De-Wen Tong, Jian-He Hu, Miao-Tao Zhang, Hung-Jen Liu*. Baculovirus surface display of Erns envelope glycoprotein of classical swine fever virus. Journal of Virological Methods, 2008, 153(2): 149-155. (IF=2.133)

科研項目

1. 畜禽重大疫病口服基因工程活載體疫苗的研製.陝西省自然科學基金.課題編號:2006C111. 2006-2008,2.0萬元,主持。

2. 豬瘟病毒p80蛋白致豬源細胞系病變機制的研究. 農業部畜禽病毒學重點開放實驗室課題. 2005-2006,2.0萬元,主持。

3. 豬瘟基因工程細胞苗的研製. 西北農林科技大學科研專項經費, 2005-2007,1.0萬元,主持。

4. 豬瘟病毒p80蛋白致豬源細胞系病變機制的研究.西北農林科技大學科研啟動(配套)經費,2005 -2007,3.0萬元,主持。

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