段明星

段明星

段明星,男,教授,清華大學。

基本信息

人物經歷

1970年,清華大學 學士。

1984年,清華大學 碩士。

現任清華大學教授,清華大學(生物科學與技術系)-隆力奇生物科技研究所所長。

研究方向

主要科研領域與方向:多肽蛋白質藥物及核酸疫苗的研究:

■ 多肽蛋白質藥物的性質及功能;

■ 多肽蛋白質藥物的口服及緩釋;

■ 核酸疫苗的構建及免疫機理和免疫途徑。

主要貢獻

Selected Publications:

■F.F.Zhuang, R.Liang, C.T.Zou, H.Ma, C.X.Zheng, M.X.Duan*.“High efficient encapsulation of plasmid DNA in PLGA microparticles by organic phase self-emulsification”, J.Biochem.Biophys.Methods 52 (2002) 169-178.

■ Bin Deng, Zheng Liu, Guoan Luo*, Hong Ma, Mingxing Duan*.“Rapid quantitative determination and assessment of insulin in oil formulation by micellar electrokinetic capillary chromatography”, Journal of Pharmaceutical and Biomedical Analysis. 27 73 - 80 (2002).

■ Liang Rong,Zhuang FengFeng, Meng Zheng, Zheng Changxue, Duan Mingxing*.“A New Potent Route of DNA Vaccine Inoculation: DNA-Liposome Complexes on Bare Skin Induce Antigen-Special Antibody Responses”, Molecules 8, 120 126. (2003).

■Hong-Wei Wang, Yong Chen, Hsiuchin Yang, Xianchuan Chen, Ming-Xing Duan, Phang C. Tai* and Sen-Fang Sui*.“Ring Like Pore Structures of SecA: Implication for Bacterial Protein-Conducting Channels”. Proc.Natl.Acad.Sci.U.S.A. Vol.100 No.7 P4221-4226 (2003).

■ Xi-Ming Qin,Ming-Xing Duan*, Bin Deng, Xi-Cheng Liu, Qiang-Zhe Zhang, Zheng Liu, and Hong-Xuan He.“Isolation and Identification of a New Thymic Peptide from Calf Thymus”, Biochemistry(Moscow) 2004, 69(8): 921-925.

■HongXuan HE, BaoHua ZHAO, LiYan LIU,Kai ZHOU, XiMing QIN, QiangZhe ZHANG, Xi LI, ChangXue ZHENG, and MingXing DUAN*.“The Humoral and Cellular Immune Responses in Mice Induced by DNA Vaccine Expressing the Sporozoite Surface Protein of Cryptosporidium parvum”, DNA AND CELL BIOLOGY Vol.23, No.5, P335-339 (2004).

■ Zhang Qiang-Zhe, Qin Xi-Ming,Dong Hai-Li, Liang Rong, He Hong-Xuan,Li Xi, Jiang Bei-Yu, Liu Xiang-Jun, Duan Ming-Xing*.“Efficient Protection of H5N1 Influenza Virus DNA Vaccine Delivering by Electroporation in Mammalian and Avian System”, Progress in Biochemistry and Biophysics Vol.32 No.8 p726-733 (2005).

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