廈門大學生物醫學研究院教授
王團老博士,教授。1999年於廈門大學生物系獲博士學位,1999年至2007年在新加坡科技研究局屬下的分子與細胞生物學研究院從事博士後研究、高級研究學者;2006年起擔任廈門大學生物醫學研究院教授,細胞生物學與傳染性疾病研究中心執行主任。現任中國細胞生物學會會員,國家自然科學基金通訊評審專家,並主持和參與多項國家級科研項目。主要從事細胞生物學、生物醫學領域的研究,特別是對動物細胞中蛋白質分子的跨膜運輸調控機制,蛋白質運輸與細胞信號轉導以及腫瘤發生等的內在聯繫及調控機制方面取得許多重要研究成果,其研究成果發表於EMBO J、Molecular Biology of Cell等國際前沿科技雜誌。
主要科研論文
Wang T, Hong W. RILP interacts with VPS22 and VPS36 of ESCRT-II and regulates their membrane recruitment. Biochem Biophys Res Commun. 2006 Nov 17;350(2):413-23.
Terebiznik MR, Vazquez CL, Torbicki K, Banks D, Wang T, Hong W, Blanke SR, Colombo MI, Jones NL. Helicobacter pylori VacA toxin promotes bacterial intracellular survival in gastric epithelial cells.Infect Immun. 2006 Dec;74(12):6599-614
Wang T, Hong W. Assay and functional properties of Rab34 interaction with RILP in lysosome morphogenesis. Methods Enzymol. 2005;403:675-87.
Wu M*, Wang T*, Loh E, Hong W, Song H. Structural basis for recruitment of RILP by small GTPase Rab7.EMBO J. 2005 Apr 20;24(8):1491-501.. (*these authors contributed this work equally)
Wang T, Wong KK, Hong W. A unique region of RILP distinguishes it from its related proteins in its regulation of lysosomal morphology and interaction with Rab7 and Rab34.Mol Biol Cell. 2004 Feb;15(2):815-26.
Tai G, Lu L, Wang TL, Tang BL, Goud B, Johannes L, Hong W. Participation of the syntaxin 5/Ykt6/GS28/GS15 SNARE complex in transport from the early/recycling endosome to the trans-Golgi network.Mol Biol Cell. 2004 Sep;15(9):4011-22
Wang T, Hong W. Interorganellar regulation of lysosome positioning by the Golgi apparatus through Rab34 interaction with Rab-interacting lysosomal protein. Mol Biol Cell. 2002 Dec;13(12):4317-32

