人物簡介
梅志剛，現任中國生理學會會員、中國針灸學會會員，宜昌市中西醫結合學會常務理事、宜昌市中醫藥學會理事，宜昌市中醫藥學會針灸分會副主委；宜昌市中醫醫院特聘專家，《Trails》、《Acupuncture in medicine》、《中國組織工程研究與臨床康復》和《中國全科醫學》雜誌審稿人。主持或參加國家自然科學基金等各級項目13項，發表學術論文70餘篇，其中被SCI/EI收錄14篇，CSCD或中文核心期刊論文50餘篇；主編或參編專著4部；申報國家專利11項，其中授權發明專利2項，實用新型專利1項。獲中國中西醫結合學會科技進步獎三等獎1項，湖北省科技進步三等獎2項，宜昌市科技進步二等獎2項，中國中醫科學院科技進步獎一等獎1項。
主要研究方向
中醫藥及針灸防治神經內科疾病機制研究
學習經歷
2011.11-2012.05 美國韋恩州立大學醫學院訪問學者；
2004.09-2007.07 中國中醫科學院獲醫學博士學位；
2001.09-2004.06 湖南中醫藥大學獲醫學碩士學位；
1996.09-2001.06 三峽大學醫學院獲中醫學學士學位
主要工作經歷
2014.01 至今 三峽大學科學技術處副處長；
2015.11 至今 三峽大學醫學院教授，碩士研究生導師；
2010.09 至今 三峽大學針灸研究所副所長；
2009.08 至今 三峽大學國家中醫藥管理局中藥藥理三級科研實驗室副主任；
2009.01 至今 宜昌市中醫醫院受聘副主任醫師、主任醫師。
主要代表文章
[1] Jin-feng Wang, Zhi-gang Mei*, Yang Fu, Song-bai Yang, Shi-zhong Zhang, Wei-feng Huang, Li Xiong, Hua-jun Zhou, Wei Tao, Zhi-tao Feng*. Puerarin, the Chinese Pueraria lobata root extract alleviates autophagy after cerebral ischemia/reperfusion via AMPK-mTOR-UlK1 pathway. Neural Regeneration Research.2017, (accepted，IF=1.78)
[2] Liyan Peng, Ketao Mu, Aiguo Liu, liangqiang Zhou, Yueyue Gao, Imrit Tejvansh Shenoy, Zhigang Mei*, Qingguo Chen*. TaVNS at acupoints Kidney (CO10), Yidan (CO11), Liver (CO12) and Shenmen (TF4) can induce auditory and limbic cortices activation measured by fMRI. Hearing Research. doi.org/10.1016/j.heares.2017.12.003 (IF=2.9, JCR一區)
[3] Jianhua Zhong,Huajun Zhou*,Tao Tang, Hanjin Cui, Ali Yang, Qimei Zhang，Jinghua Zhou, Qiang Zhang, Xun Gong, Zhaohui Zhang, Zhigang Mei.Activation of the Notch-1 signaling pathway is involved in intracerebral hemorrhage-inducedreactive astrogliosis in rats. J Neurosurg.2017, 27:1-8. doi: 10.3171/2016.11.JNS162121.（IF=4.06）
[4]Zhi-tao Feng, Juan Xu, Guo-chao He, San-jin Cai, Juan Li*, Zhi-gang Mei*. A systemic review and meta-analysis of the clinical efficacy and safety of total glucosides of peony combined with methotrexate in rheumatoid arthritis. Clin Rheumatol.2017, DOI 10.1007/s10067-017-3770-y. (IF=2.36)
[5]Zhigang Mei*, Lingjing Tan, Jinfeng Wang, et al. Fermented Chinese formula Shuan-Tong-Ling attenuates apoptosis and inflammation by activating SIRT1 in experimental stroke rats. Neural Regeneration Research.2017,12(3):425-432. (IF=1.78)
[6] Qing-hua Zheng, Xiao-li Li, Zhi-gang Mei*, Qing-xian Mei, Jin-feng Wang, Ling-jing Tan, Song-bai Yang, Zhi-tao Feng*. Efficacy and safety of puerarin injection in curing acute ischemic stroke: A meta-analysis of randomized controlled trials. Medicine.2017, 96(1): e5803 (IF=1.80)
[7] Chunpeng Wan, Fen Jin, Youqin Du, Kang Yang, Liangliang Yao, Zhigang Mei*, Weifeng Huang. Genistein Improves Schistosomiasis Liver Granuloma and Fibrosis via Dampening NF-kB Signaling in Mice. Parasitology Research.2017,DOI 10.1007/s00436-017-5392-3 (IF=2.03)
[8] Lingjing Tan, Xiang Zhang, Zhigang Mei*, Jinfeng Wang, Xiaoli Li, Weifeng Huang, and Songbai Yang. Fermented Chinese formula Shuan-Tong-Ling protects brain microvascular endothelial cells against oxidative stress injury. Evidence based complementary and alternative medicine.2016,2016: 5154290. doi.org/10.1155/2016/5154290 (SCI, IF=1.93)
[9] Tian-Tian Li, Zhao-Jun Wang, Song-bai Yang, Jun-Hong Zhu, Shi-Zhong Zhang, San-Jin Cai, Wen-Han Ma, Ding-Qi Zhang, Zhi-Gang Mei*. Transcutaneous electrical stimulation at auricular acupoints innervated by auricular branch of vagus nerve pairing tone for tinnitus: study protocol for a randomized controlled clinical trial. Trials,2015,16:101. doi:10.1186/s13063-015-0630-4 (IF=1.86)
[10] Mahmood G, Mei Z, Hojjat H, Pace E, Zhang J*. Therapeutic effect of sildenafil on blast-induced tinnitus and auditory impairment. Neuroscience. 2014,269:367-382. (IF=3.36)
[11] Xiaojie Liu, Zhigang Mei*, Jingping Qian, et al. Puerarin counteracts inflammatory response after cerebral ischemia/reperfusion in rats through activating cholinergic anti-inflammatory pathway. Neural Regeneration Research.2013,8(34): 3203-3215. (SCI)
[12] MEI Zhi-gang*, CHENG Chuan-guo, ZHENG Jun-feng. Observations on curative effect of High-frequency Electric Sparkle and Point-injection Therapy on knee osteoarthritis. Journal of Traditional Chinese Medicine.2011, 31(4): 311-315. (SCI).
[13] Mei Zhi-gang*, Zeng Yong-bao, Liu Xiao-jie, et al. Efficacy of auricular acupuncture on inflammatory markers and insulin resistance in type 2 diabetes model of rats: in light of cholinergic anti-inflammatory pathway.In: proceedings 2011 International Conference on Human Health and Biomedical Engineering[C], New Jersy, IEEE. 2011:1236-1241.(EI )
[14] WANG Jin-feng, TAN Ling-jing, MEI Qing-xian, ZHENG Qing-hua, YANG Song-bai, MEI Zhi-gang*. Meta analysis on acupuncture in treatment of postpartum depression. World journal of acupuncture-moxibusiton.2017, 27(1):37-43.（ESCI）
[15] YU Huan, CHENG Jun-ping*, ZHANG Ding-qi, TANG Cui-juan, HUANG Kun-yan, TAN Ling-jing, YANG Song-bai, MEI Zhi-gang*. Effect of acupuncture combined with Chinese medicine on the expression of interstitial cells of Cajal, substance P and nerve nitric oxide synthase in diabetic mice with gastroparesis antrum. World Journal of Acupuncture- Moxibustion.2015,25(3):35-42. (ESCI)
[16] 陶薇，王凱，王金鳳，馮知濤*， 梅志剛*.民族藥藍布正活性成分及藥理作用研究進展.中草藥. 2018, 49(1):233-238.
[17] 陶薇,王金鳳,譚凌菁,馮知濤,蔡三金,周華軍, 梅志剛 *.基於內質網應激的中醫藥防治腦缺血再灌注機制研究.時珍國醫國藥. 2017, 28(9):2218-2221.
[18] 張翔,劉從國,張繼紅,焦良波,李小麗,胡衛, 梅志剛 *.益氣活血中藥聯合西醫治療急性缺血性腦卒中的meta分析.中國老年學雜誌. 2017, 37 (4): 873-876.
[19] 梅志剛,譚凌菁.從辨證論治看中醫在我國精準醫療計畫中的作為.中華中醫藥雜誌. 2016，31（10）：3887-3890.
[20] 譚凌菁,王金鳳, 梅志剛 *.沉默信息調節因子1信號通路在腦缺血-再灌注損傷中的保護作用.中國腦血管病雜誌.2016,13(8):442-445.
[21] 唐翠娟,程軍平,張定棋, 梅志剛 *,黃坤艷,喻歡,楊松柏,譚凌菁.針藥結合對糖尿病胃輕癱小鼠胃竇Cajal間質細胞超微結構的影響.中華中醫藥雜誌.2016,31(7):2518-2521.
[22] 楊松柏, 梅志剛 *,譚凌菁,等.耳迷走神經分布區穴位電刺激配合聲音掩蔽法對耳鳴大鼠聽性腦幹反應及下丘神經遞質的影響.中國針灸. 2016，36（5）：517-522.
[23] 張定棋,馬文翰, 梅志剛 *,等.基於文獻的補益類中藥臨床套用不良反應分析.中國中醫藥信息雜誌.2015,22(6):43-45.
[24]劉曉潔, 梅志剛 *.耳鳴的發生機制與迷走神經刺激調節作用.中國老年學雜誌.2014,34(6): 1698-1702.
[25]何靜,蔣斌, 梅志剛 *.中樞神經可塑性變化與耳鳴發生機制研究進展.中國全科醫學,2014,17 (8):955-959.
[26] 楊松柏, 梅志剛 *,蔡三金,等.不同穴位組合針刺法對女性更年期失眠症的療效比較：隨機對照研究.中國針灸.2014,34(1):3-8.
