![曹巍[上海九院口腔頜面外科專家]](/img/4/845/nBnauM3XwUTOygzM5gjM1kTO0UTMyITNykTO0EDMwAjMwUzL4IzL1UzLt92YucmbvRWdo5Cd0FmLxE2LvoDc0RHa.jpg "曹巍[上海九院口腔頜面外科專家]")
研究方向
口腔癌的臨床和基礎研究
口腔癌的分子分型研究
任職
任職如下 ：
上海口腔醫學會口腔頜面-頭頸腫瘤醫學專委會青年委員
中國臨床腫瘤學會頭頸專委會委員
國際口腔頜面外科協會(ICOMS) Member
國際牙科研究協會(IADR) Member
上海市級醫院肉瘤臨床診治中心分中心秘書
美國癌症研究協會(AACR) Member
科研項目
科研項目如下 ：
| 項目編號 | 項目名稱 | 課題來源 | 起止年月 | 批准經費 | 承擔職責 |
| YG2016MS05 | 口腔鱗癌早期診斷相關 長鏈非編碼RNA譜型的篩選和鑑定 | 上海交通大學多學科交叉項目培育(醫工)面上 | 2017-01~2019-12 | 21萬元 | 課題負責人 |
| 81672745 | FHL1-RGS2-DDB1E3連線酶信號通路在口腔鱗癌發生、進展中作用機制研究 | 國家自然基金面上項目 | 2017-01~2020-12 | 61萬元 | 課題負責人 |
| 2016YFC0902703 | 口腔癌防治靶點和分子標誌物的篩選和驗證 | 科技部國家重點研發計畫子課題 | 2016-07~2018-12 | 30萬元 | 課題負責人 |
| 81202130 | 組蛋白甲基轉移酶EZH2介導的FHL1基因表觀遺傳學沉默在口腔鱗癌發生中作用和機制研究 | 國家自然基金青年項目 | 2013-01~2015-12 | 23萬元 | 課題負責人 |
學術論文
部分已發表英文論文如下 ：
| 作者 | 論文標題 | 期刊名 | 出版年 | 卷期頁碼 |
| Ong HS, Gokavarapu S, Tian Z, Li J,Cao W（通訊作者）, Zhang CP | Does a mandibular access osteotomy improve survival in pT2 oral tongue cancers? Retrospective study at a single institution | Int J Oral Maxillofac Surg | 2018 | 47(3):289-295 |
| Shen Q, Chen Y, Gokavarapu S,Cao W（通訊作者）, Ji T | Primary intraosseous squamous cell carcinoma of the mandible: locoregional control and survival is significantly reduced if the tumour is more than 4cm in size | Br J Oral Maxillofac Surg | 2018 | 56(1):48-53 |
| Liu J, Xing Y, Xu L, Chen W,Cao W（通訊作者）, Zhang C | Decreased expression of pseudogene PTENP1 promotes malignant behaviours and is associated with the poor survival of patients with HNSCC | Sci Rep | 2017 | 7:41179 |
| Wang X,Cao W, Zhang J, Yan M, Xu Q, Wu X, Wan L, Zhang Z, Zhang C, Qin X, Xiao M, Ye D, Liu Y, Han Z, Wang S, Mao L, Wei W, Chen W | A covalently bound inhibitor triggers EZH2 degradation through CHIP-mediated ubiquitination | EMBO J | 2017 | 36(9):1243-1260 |
| Yang R, Liu Z, Peng C,Cao W（通訊作者）, Ji T | Maxillary ameloblastoma: Factors associated with risk of recurrence | Head Neck | 2017 | 39(5):996-1000 |
| Yang R, Liu Z, Gokavarapu S, Peng C, Ji T,Cao W（通訊作者） | Recurrence and cancerization of ameloblastoma: multivariate analysis of 87 recurrent craniofacial ameloblastoma to assess risk factors associated with early recurrence and secondary ameloblastic carcinoma | Chin J Cancer Res | 2017 | 29(3):189-195 |
| Cao W, Liu JN, Liu Z, Wang X, Han ZG, Ji T, Chen WT, Zou X | A three-lncRNA signature derived from the Atlas of ncRNA in cancer (TANRIC) database predicts the survival of patients with head and neck squamous cell carcinoma | Oral Oncol | 2017 | 65:94-101 |
| Lin C,Cao W（共同第一作者）, Ren Z, Tang Y, Zhang C, Yang R, Chen Y, Liu Z, Peng C, Wang L, Wang X, Ji T | GDNF secreted by nerves enhances PD-L1 expression via JAK2-STAT1 signaling activation in HNSCC | Oncoimmunology | 2017 | 6(11):e1353860 |
| Cao W, Liu Z, Gokavarapu S, Chen Y, Yang R, Ji T | Reformed smokers have survival benefits after head and neck cancer | Br J Oral Maxillofac Surg | 2016 | 54(7):818-25 |
| Cao W, Liu J, Xia R, Lin L, Wang X, Xiao M, Zhang C, Li J, Ji T, Chen W | X-linked FHL1 as a novel therapeutic target for head and neck squamous cell carcinoma | Oncotarget | 2016 | 7(12):14537-50 |
| Chen Y,Cao W（共同第一作者）, Gao X, Ong H, Ji T | Predicting postoperative complications of head and neck squamous cell carcinoma in elderly patients using random forest algorithm model | BMC Med Inform Decis Mak | 2015 | 15:44 |
| Liu J,Cao W（共同第一作者）, Chen W, Xu L, Zhang C | Decreased expression of Kallmann syndrome 1 sequence gene (KAL1) contributes to oral squamous cell carcinoma progression and significantly correlates with poorly differentiated grade | J Oral Pathol Med | 2015 | 44(2):109-14 |
| Gupta A,Cao W（共同第一作者）, Sadashivaiah K, Chen W, Schneider A, Chellaiah MA | Promising noninvasive cellular phenotype in prostate cancer cells knockdown of matrix metalloproteinase 9 | ScientificWorldJournal | 2013 | 2013:493689 |
| Cui Z,Cao W（共同第一作者）, Li J, Song X, Mao L, Chen W | TRIM24 overexpression is common in locally advanced head and neck squamous cell carcinoma and correlates with aggressive malignant phenotypes | PLoS One | 2013 | 8(5):e63887 |
| Zhang S,Cao W（共同第一作者）, Wei K, Liu X, Xu Y, Yang C, Undt G, Haddad MS, Chen W | Expression of VEGF-receptors in TMJ synovium of rabbits with experimentally induced internal derangement | Br J Oral Maxillofac Surg | 2013 | 51(1):69-73 |
| Cao W, Feng Z, Cui Z, Zhang C, Sun Z, Mao L, Chen W | Up-regulation of enhancer of zeste homolog 2 is associated positively with cyclin D1 overexpression and poor clinical outcome in head and neck squamous cell carcinoma | Cancer | 2012 | 118(11):2858-71 |
| Cao W, Ribeiro Rde O, Liu D, Saintigny P, Xia R, Xue Y, Lin R, Mao L, Ren H | EZH2 promotes malignant behaviors via cell cycle dysregulation and its mRNA level associates with prognosis of patient with non-small cell lung cancer | PLoS One | 2012 | 7(12):e52984 |
| Cao W, Younis RH, Li J, Chen H, Xia R, Mao L, Chen W, Ren H | EZH2 promotes malignant phenotypes and is a predictor of oral cancer development in patients with oral leukoplakia | Cancer Prev Res (Phila) | 2011 | 4(11):1816-24 |
| Cao W, Zhang ZY, Xu Q, Sun Q, Yan M, Zhang J, Zhang P, Han ZG, Chen WT | Epigenetic silencing of MAL, a putative tumor suppressor gene, can contribute to human epithelium cell carcinoma | Mol Cancer | 2010 | 9:296 |
部分已發表中文論文如下 ：
[1] 兔TMJ ID模型關節滑膜組織的顯微及超微結構觀察[J]. 張善勇,劉秀明,黃棟,曹巍,楊馳,萬澎波,惲白.中國口腔頜面外科雜誌 . 2011(04) 82
[2] 3種VEGF受體亞型在兔TMJ結構紊亂模型滑膜組織中的表達[J]. 張善勇,魏魁傑,曹巍,劉秀明,楊馳,惲白,陳琢之.中國口腔頜面外科雜誌 . 2009(05) 81
[3] nm23-h1基因對口腔鱗癌細胞增殖及PKC-α表達的影響[J]. 楊菲,陳萬濤,曹巍,嚴明,周曉健,張萍.北京口腔醫學 . 2009(04) 74
[4] 術前全身合併症情況及營養狀態對老年口腔鱗癌患者預後的影響[J]. 劉喆麒,曹巍,任振虎,彭燦邦,季彤,王悅平.中國口腔頜面外科雜誌 . 2017(03) 65
[5] 口腔頜面-頭頸部鱗癌分子發病機制研究進展[P]. 陳萬濤,張萍,徐駸,嚴明,張建軍,王旭,曹巍. . 2014 45
[6] DNA高甲基化失活的MAL基因參與了口腔鱗癌的發生[P]. 陳萬濤,曹巍. . 2011 40
[7] 成釉細胞瘤的復發與惡變:87例復發頜骨成釉細胞瘤危險因素分析[P]. 楊嶸,劉喆麒,唐漁,彭燦邦,林承重,任振虎,曹巍,季彤. . 2017 36
[8] 由PBL教學演化的口腔臨床免疫學實驗教學新模式探討[P]. 嚴明,張建軍,張萍,徐駸,曹巍,陳萬濤. . 2013 34
[9] 缺氧誘導因子1α在成釉細胞瘤中的表達及意義[J]. 唐漁,曹巍,彭燦邦,劉喆麒,林承重,季彤.中國口腔頜面外科雜誌 . 2018(04) 33
[10] Contactin-1在口腔鱗癌中的表達意義及其作用[P]. 武和明,曹巍,李懷奇,丁旭,任國欣,郭偉,陳萬濤,吳煜農. . 2011 30
11、口腔頜面頭頸鱗癌相關基因TGM3,OPN,MAL和LAGY的功能研究進展 曹巍陳萬濤 張萍 口腔頜面外科雜誌 2007, 17(4)
