宣利江

宣利江

中科院上海藥物所研究員、博士生導師、研究組長

基本信息

基本信息

1990 年畢業於上海醫科大學;

1995 年於中國科學院上海藥物研究所獲博士學位,留所任助理研究員;1996 年赴日本九州大學藥學部生藥學教室進行博士後工作;

1998 年回所工作,期間曾赴美國加州大學聖地亞哥分校 Scripps 海洋學研究所訪問研究。

研究方向

以產業化為目標,以天然藥用資源的水溶性成分研究為基礎,探索中藥的作用機理和物質基礎,尋找和發現結構新穎的天然活性化合物及先導化合物,並在此基礎上開展新藥創製和中藥現代化的研究。

專家類別

研究員

職務

中科院上海藥物所研究員、博士生導師、研究組長

承擔科研項目情況

承擔“重大新藥創製”國家科技重大專項,上海市重大產業科技攻關項目等多個課題。

獲獎及榮譽

2011年獲國家技術發明二等獎

2011年獲中國藥學發展獎傑出青年學者獎

2007年獲上海市技術發明一等獎

2006年獲中國國際工業博覽會創新獎

2006年獲上海市科教黨委系統青年科技創新人才獎

2005年獲中國科學院先進集體2004年獲上海藥學會藥學科技獎

2003年上海化學化工學會吳蘊初專項獎提名獎

代表論著

Xiao-Ping Hu, Shu-Wei Zhang, Shan-Shan Liu, and Li-Jiang Xuan. New Anthraquinone and Iridoid Glycosides from the Stems of Hedyotis hedyotidea. Helvetica Chimica Acta

Zhou Tong; Zhang Xiao-Hui; Zhang Shu-Wei; Liu Shan-Shan; Xuan Li-Jiang. New Phenylpropanoids and In Vitro α-Glucosidase Inhibitors from Balanophora japonica. Planta medica

Zhou, Tong; Zhang, Shu-wei; Liu, Shan-shan; Cong, Hai-jian; Xuan, Li-jiang. Daphnodorin dimers from Edgeworthia chrysantha with α-glucosidase inhibitory activity. Phytochemistry Letter

Chen, Li; Xuan, Li-Jiang; Wang, Yi-Ping. Effects of magnesium lithospermate B and its analogues on Ca2+ homeostasis in cultured rat thoracic aorta vascular smooth muscle cells. Planta Medica

Yu, Juan; Zhang, Hao-Hao; Yu, Qiang; Xuan, Li-Jiang. Prenylated Phenols from Sabia japonica. Helvetica Chimica Acta

Liu, Shan-Shan; Zhou, Tong; Zhang, Shu-Wei; Xuan, Li-Jiang. Chemical Constituents from Clerodendrum bungei and Their Cytotoxic Activities. Helvetica Chimica Acta

Zhang, Xiao-Hui; Liu, Shan-Shan; Xuan, Li-Jiang. Cyclopentenylglycines and other constituents from Alangium chinense. Biochemical Systematics and Ecology

Wu, Jun; Zhou, Tong; Zhang, Shu-wei; Zhang, Xiao-hui; Xuan, Li-jiang. Cytotoxic terpenoids from the fruits of Vitex trifolia L. Planta Medica

Xiao Kai, Zhang Hongjun, Xuan Lijiang, Zhang Juan, Xu Yaming, Bai Donglu. Stilbenoids: chemistry and bioactivities. Studies in natural chemistry

Xiaohui Zhang, Shuwei Zhang, Lijiang Xuan. Three new furannosesquiterpenoids from Bombax malabaricum and revised NMR assignment of Hibiscone C. Heterocycles

Shanshan Liu, Huilin Zhu, Shuwei Zhang, Xiaohui Zhang, Qiang Yu, and Lijiang Xuan. Abietane diterpenoids from Clerodendrum bungei. J. Nat. Prod

Jun Wu, Xiaohui Zhang, Shuwei Zhang, Lijiang Xuan. Three novel compounds from the flowers of Bombax malabaricum. Helvertica Chimica Act

Wang, Li; Zhang, Qiang; Li, Xiaochuan; Lu, Youli; Xue, Zhimou; Xuan, Lijiang; Wang, Yiping. Pharmacokinetics and metabolism of lithospermic acid by LC/MS/MS in rats. International Journal of Pharmaceutics

Shuwei Zhang, Lijiang Xuan. Cyclopentenone and furan derivative from mycelia of Cordyceps cicadae. The Journal of Antibiotics

Zhang, Xiao-Hui; Zhu, Hui-Lin; Yu, Qiang; Xuan, Li-Jiang. Cytotoxic cardenolides from Streptocaulon griffithii. Chemistry & Biodiversity

Zhang, Shu-Wei; Xuan, Li-Jiang. Five aromatics bearing a 4-O-methylglucose unit from Cordyceps cicadae. Helvetica Chimica Acta,

Jiang, Lili; Zhang, Shuwei; Xuan, Lijiang. Oxanthrone C-glycosides and epoxynaphthoquinol from the roots of Rumex japonicus. Phytochemistry

Zhang, Xiaohui; Zhu, Huilin; Zhang, Shuwei; Yu, Qiang; Xuan, Lijiang. Sesquiterpenoids from Bombax malabaricum. Journal of Natural Products,

Li, Xiaochuan; Yu, Chen; Wang, Li; Lu, Youli; Wang, Wenyi; Xuan, Lijiang; Wang, Yiping. Simultaneous determination of lithospermic acid B and its three metabolites by liquid chromatography/tandem mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis

Li, Xiaochuan; Yu, Chen; Lu, Youli; Gu, Yunlong; Lu, Jie; Xu, Wei; Xuan, Lijiang; Wang, Yiping. Pharmacokinetics, tissue distribution, metabolism, and excretion of depside salts from Salvia miltiorrhiza in rats. Drug Metabolism and Disposition

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